Immunofluorescent analysis of (-20℃ Ethanol) fixed HeLa cells using 15054-1-AP (AKR1A1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Various lysates were subjected to SDS PAGE followed by western blot with 15054-1-AP (AKR1A1 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours.

Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 15054-1-AP (AKR1A1 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

Various lysates were subjected to SDS PAGE followed by western blot with 15054-1-AP (AKR1A1 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours.

Immunofluorescent analysis of (-20℃ Ethanol) fixed HeLa cells using 15054-1-AP (AKR1A1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 15054-1-AP (AKR1A1 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 15054-1-AP (AKR1A1 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

3. It Wastes Fuel and Tires A wobbly or misaligned wheel caused by a bad bearing increases rolling resistance. This means your car uses more fuel to maintain the same speed. Plus, uneven tire wear shortens the lifespan of your tires, adding another expense.

Immunofluorescent analysis of (-20℃ Ethanol) fixed HeLa cells using 15054-1-AP (AKR1A1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L).

A bad wheel bearing might seem like a minor inconvenience at first—a faint humming or grinding sound coming from your wheel. But is it really something you can ignore? While it’s easy to brush off odd noises, driving with a faulty wheel bearing is a gamble that can lead to severe damage and safety risks. We'll explain what wheel bearings do, the signs of trouble, and the potential dangers of ignoring the problem.

Is your car making strange noises or handling poorly? Don’t take chances with your safety. Visit Extreme Auto Repair for a thorough inspection and professional wheel bearing replacements. Call us today to schedule your appointment!

15054-1-AP targets AKR1A1 in WB, IHC, IF/ICC, IP, ELISA applications and shows reactivity with human, mouse, rat samples.

Image

Regular inspections and maintenance are key to avoiding wheel bearing issues. Keep an eye on your tires, ensure proper wheel alignment, and avoid driving through deep water or mud, which can allow moisture to infiltrate the bearings. Catching minor issues early can save you a lot of hassle—and money.

The Proteintech guarantee covers Proteintech antibodies in any species and any application, including those not listed on the datasheet. If the antibody doesn’t perform, you can receive a hassle-free refund or credit note.

Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 15054-1-AP (AKR1A1 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

A bad wheel bearing doesn’t fail silently—it sends you signals. Recognizing these signs early can save you from costly repairs and dangerous situations:

Fixing a bad wheel bearing isn’t a DIY job. It requires specialized tools, precise measurements, and a lot of expertise. Our professional can inspect the bearing, determine the extent of the damage, and replace it if needed. The good news? Replacing a wheel bearing is a relatively straightforward repair when caught early.

The short answer? You shouldn’t. Driving with a bad wheel bearing isn’t just risky; it’s a disaster waiting to happen. Here’s why:

1. It Compromises Your Safety A faulty wheel bearing can lead to unpredictable handling. You may experience a loss of control, particularly when turning or braking. Worst-case scenario? The bearing could fail completely, causing the wheel to detach. That’s not a chance you want to take on busy roads.

Since they’re designed to handle heavy loads and high speeds, wheel bearings are built tough. But they’re not invincible. Over time, wear and tear, poor road conditions, and even moisture can take a toll, leading to damage or failure.

At its core, a wheel bearing is a small but critical component located at the hub of your wheel. Its job? To allow your wheel to rotate while supporting the vehicle’s weight. This part consists of steel balls or rollers encased in a metal ring, lubricated to reduce friction.

Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 15054-1-AP (AKR1A1 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

There’s no definitive answer, as the lifespan of a failing bearing depends on the severity of the damage and your driving conditions. That said, the moment you notice signs of trouble, it’s best to address the issue immediately. Driving with a bad wheel bearing is a ticking time bomb—one that can go off unexpectedly.

Image

Image

Various lysates were subjected to SDS PAGE followed by western blot with 15054-1-AP (AKR1A1 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours.

4. It Can Leave You Stranded Wheel bearing failure isn’t the kind of issue that gives you weeks of warning. If the bearing seizes or breaks apart, you could find yourself stuck on the side of the road—possibly with a wheel that’s no longer attached to the car.

Contact Us Privacy Policy Terms of use Terms and Conditions Trademark Information Imprint (Impressum) Modern Slavery Statement

English Czech Danish German Spanish Finnish French Hungarian Italian Lithuanian Dutch Norwegian-Bokmol Polish Portuguese Slovak Swedish

At Proteintech, we pride ourselves on our antibody quality, customer service and transparency. As such, we are comparing our antibodies with other vendors, enabling easy identification and comparisons of key data to help you choose the suitable antibody for your needs.

2. It Causes More Damage Ignoring the issue doesn’t make it go away—it makes it worse. A bad bearing can strain other components like the hub assembly, CV joint, and even the suspension system. The longer you drive with the problem, the more expensive the repairs become.

Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 15054-1-AP (AKR1A1 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).