If you hear a clicking sound that increases in frequency as the vehicle accelerates, there could be a problem with the wheel hub assembly.

The risk of sleepiness and reduced alertness or concentration may be increased if you drink alcohol while taking prochlorperazine. It is best to limit the amount of alcohol you drink.

Uncontrolled Movements. Prochlorperazine can cause some people to have movements that they cannot control. This condition, called tardive dyskinesia (TD), can cause jerky movements of your face, tongue, or body. TD can be permanent. Call your healthcare provider right away if you have any symptoms of TD.

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Prochlorperazine may cause false-positive results on a pregnancy test. This means the test may say you are pregnant when you are not pregnant. If you have a positive pregnancy test when taking prochlorperazine, talk to your healthcare provider about how to confirm whether or not you are really pregnant.Â

Restlessness. Prochlorperazine may cause restlessness, jitteriness, agitation, or possibly trouble sleeping. Tell your healthcare provider right away if you have these symptoms.Â

If one tire wears out faster than the others, it could be a sign that the wheel bearings are worn. However, it also could be a sign the tire is improperly inflated (too much air pressure or not enough), the tires are improperly aligned, or the vehicle has damaged or worn suspension components.

The anti-lock warning light may illuminate if the ring, tire, and wheel wobble, the wheel’s speed sensor is no longer operating properly, and the ABS may operate sporadically or not at all. See a professional for repair.

While less common, the most serious side effects of prochlorperazine are described below, along with what to do if they happen.

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Eye Effects. Prochlorperazine may have effects on your eyes, such as deposits on the cornea and lens. This may be more likely if you take higher doses of prochlorperazine, or if you take prochlorperazine for a longer period of time. Your healthcare provider may recommend that you have your eyes examined regularly while taking prochlorperazine. Tell your healthcare provider right away if you have eye discomfort or changes in your vision.

Prochlorperazine belongs to a group of medicines called first-generation (typical) antipsychotics. It blocks some areas in the brain where the natural chemical, dopamine, works. This lowers the effect of dopamine in the body. Dopamine affects your behavior and thinking. Plus, dopamine can trigger vomiting.

The most easily identifiable and common symptom of bad wheel bearings is audible. But it can be confusing. For example, the source of a humming noise can be linked to other issues, such as tires and the CV joint.

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High Prolactin Level (Hyperprolactinemia). Prochlorperazine may cause an increased level of the hormone prolactin in your blood. Increased levels of prolactin could lead to fertility or bone problems. Contact your healthcare provider if you have any of the following symptoms.

Blood Disorders. Prochlorperazine can cause blood disorders, such as agranulocytosis, low neutrophil levels (neutropenia), and low white blood cell levels (leukopenia). Keep all appointments to have your blood checked. Call your healthcare provider right away if you have any of the following symptoms of blood disorders.

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and only take the next dose. Do not take double or extra doses.

Prochlorperazine can make your skin more sensitive to light from the sun, sunlamps, and tanning beds. This is called photosensitivity. Exposure to this light can cause severe sunburns, blisters, and swelling. If you need to be in sunlight, wear sunscreen, a hat, and clothing that covers your skin.

The typical sounds of worn-out wheel bearings are squealing and/or growling. The sound intensifies as vehicle speed increases. Try to pinpoint the location of the noise because it will identify the location of the worn-out bearings.

Tell your healthcare provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are taking. This will help them determine if prochlorperazine is right for you.

Technicians can check for wheel wobble by putting the vehicle on a lift and manually checking for wheel movement. Typically, it would be impossible to shake the wheel and tire. However, if it moves, the hub assembly needs immediate attention. The tire and wheel can literally come off the vehicle at any time, at any speed, if you don’t repair your vehicle.

There may be other side effects of prochlorperazine that are not listed here. Contact your healthcare provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088. In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.

People 65 and older can be at greater risk for some side effects from prochlorperazine. Talk to your healthcare provider about your risks if you are in this age group.

Editor’s Note: This article has been updated for accuracy since it was originally published. Rick Kranz contributed to this report.

Liver Damage. Liver damage, also called hepatotoxicity, can happen when taking prochlorperazine. Call your healthcare provider right away if you have any of the following symptoms of liver damage.

Overview: Prochlorperazine is used to treat schizophrenia, anxiety, or severe nausea and vomiting. It belongs to a group of medicines called first-generation (typical) antipsychotics. Common side effects include blurred vision, constipation, dizziness, and drowsiness. Serious side effects may include uncontrolled movements, blood disorders, and low blood pressure upon standing.

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Your vehicle will signal that it’s time to replace a failed wheel bearing. For example, if you hear unusual sounds like humming or clicking, then your bearing might be bad. Watch out and listen for these signs and symptoms:

Prochlorperazine is also available in a suppository form that is inserted into the rectum. See Prochlorperazine rectal for more information.

Oral Tablet. Prochlorperazine tablets should be stored at room temperature, between 68 F to 77 F (20 C to 25 C). It can be exposed to temperatures between 59 F to 86 F (15 C to 30 C) for shorter periods of time, such as when transporting it. Store in a cool, dry place, in a tight, light-resistant container.

If you or someone else has used too much prochlorperazine, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222.

Immune System Reactions. Prochlorperazine can cause inflammation of your liver, blood vessels, or lymph vessels, and can cause symptoms that look like a condition called lupus. Stop taking prochlorperazine and call your healthcare provider right away if you develop any of the following symptoms.

Imagine driving on the freeway when the left front tire and wheel suddenly break off, sending your out-of-control vehicle skidding across several lanes of 65 mph traffic. This is not an exaggeration. This is reality, and can happen if you fail to notice the signs the wheel bearings are deteriorating and need immediate repairs. Your wheel bearing might be bad if you hear unusual sounds like humming, squeaking, or clicking. Some experts say a bad wheel bearing can sound like a bird chirping. Also, if your car wobbles or pulls to one side, you will want to get it checked.

Parkinson-like Symptoms. Prochlorperazine may cause involuntary movement problems, including shakiness, stiffness, or jerkiness. It can also cause drooling, falling, or walking or balance problems. These are called Parkinson-like symptoms, or parkinsonism. Call your healthcare provider right away if you develop any Parkinson-like symptoms.

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However, luxury cars are more expensive to repair. Do note that if bearings go bad at one wheel, replacing the bearings at the other wheel on the same axle is unnecessary. Don’t let someone talk you into work that is not needed. Get the price estimate for wheel bearing replacement for your make and model of car.

Certain Children. Prochlorperazine should not be used in certain children, such as those under two years old or who weigh less than 20 pounds.Â

Low Blood Pressure Upon Standing (Orthostatic Hypotension) and Falls. Prochlorperazine may cause a sudden drop in blood pressure when standing up. To help prevent this, be careful not to get up too quickly. If you feel faint or dizzy, sit or lie down right away until the dizziness stops, then take your time getting up again. Tell your healthcare provider right away if you have any of the following symptoms of orthostatic hypotension.

Pregnancy. It is not known if or how prochlorperazine could affect pregnancy or harm an unborn baby. Taking prochlorperazine during the third trimester of pregnancy could cause a newborn baby to have symptoms such as agitation, breathing problems, or trouble feeding. Tell your healthcare provider if you are or plan to become pregnant. Your healthcare provider will advise you if you should take prochlorperazine while you are pregnant or trying to get pregnant.

Psychosis Related to Dementia. There is a higher risk of death in older adults who take prochlorperazine or another antipsychotic and have psychosis related to dementia. Prochlorperazine is not approved to treat dementia-related psychosis.

Bad wheel bearings can cause the steering wheel to vibrate. The intensity increases as the vehicle speed increases and the vehicle turns to the left or right. However, the vibration could be linked to an out-of-round tire (there could be a flat spot on the tire) or a tire that is no longer balanced. Another cause is damaged or worn suspension components.

Wheel bearings are theoretically engineered to last the life of the vehicle. There is no maintenance schedule for replacing wheel bearings, and there is no constant source of lubrication. However, they can be damaged, leading to failure.

Other Medicines and Supplements. Prochlorperazine may interact with other medicines and supplements. Before using prochlorperazine, tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. See the Interactions section for more details.

The original equipment bearings on your vehicle are engineered for specific loads. Those bigger and wider tires look cool, as do tires with lower tread walls. But they place higher loads on the wheel bearings, possibly resulting in accelerated wear. That could present a safety issue if your wheel bearings fail.

Most vehicles today use sealed hub bearing assemblies that contain roller bearings. While we don’t address these, older cars used tapered roller bearings, which required servicing and preload adjusting to ensure the right amount of end play or axial clearance.

Do not stop taking prochlorperazine without talking to your healthcare provider. Stopping too quickly may cause serious side effects. Call your healthcare provider right away if you have any of the following symptoms.

“The good news is most of the time, a vehicle will let you know way before a failure ever happens,” said Gary Hardesty, Kelley Blue Book’s in-house service and maintenance expert and an A.S.E. certified master technician. “The key is to listen to your car. Most times, a failing wheel bearing will exhibit a growling type of noise that changes with vehicle speed. The faster the car (goes), the faster the frequency of the growl.”

The cost to replace one front-wheel hub assembly varies widely. Among the variables are the vehicle brand and model, the garage’s labor rate, and the cost of parts. The average out-the-door wheel bearing replacement cost without taxes is about $350 per wheel.

Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are taking.

Wheel bearings connect a car’s wheels to the axles. They allow wheels to turn with minimal friction. Though wheel bearings are low-maintenance parts, they are important safety components of a vehicle’s braking, steering, and suspension systems. The one-piece hub assembly, between the drive axle and the brake disc or drums, incorporates the hub, wheel bearings, ABS (anti-lock braking system) wheel speed sensor, and mounting flange.

Severe Allergic Reactions. Prochlorperazine may cause allergic reactions, which can be serious. Stop using prochlorperazine and get help right away if you have any of the following symptoms of a serious allergic reaction.

The most common side effects of prochlorperazine are listed below. Tell your healthcare provider if you have any of these side effects that bother you.

Hardesty cautions that if you think something is wrong, don’t wait to get it diagnosed: “The longer you wait, the more it will cost as other components may be damaged by a wheel bearing.”

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Breastfeeding. Prochlorperazine passes into breast milk. Tell your healthcare provider if you are breastfeeding or plan to breastfeed.

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Prochlorperazine can affect your alertness or coordination. Do not drive or do other activities that require alertness or coordination until you know how prochlorperazine affects you.

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The bearings are tightly packed in a grease-filled, waterproof, sealed metal ring. This housing, called a race, is located inside the hub, and each wheel has one. Wheel bearings have a Herculean responsibility: They are engineered to support the vehicle’s entire weight.

Driving with bad wheel bearings impacts the safety of a vehicle, and it could cause a serious car accident. We do not advise driving on them when they fail and recommend getting them checked out as soon as possible. Bad wheel bearings can damage things like your hub, the vehicle’s constant velocity joint (CV joint), or the automatic transmission.

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Worn bearings may cause a vehicle to pull to the left or right when brakes are applied. The direction the vehicle pulls signals where the worn bearings are located, on the left or right side of the vehicle. However, this can also signal brake rotor or brake caliper problems.

Neuroleptic Malignant Syndrome (NMS). Antipsychotic medicines, like prochlorperazine, can cause a rare but serious condition called neuroleptic malignant syndrome. NMS can lead to death. Stop using prochlorperazine and call your healthcare provider right away if you have any of the following symptoms.

This may not be a complete list of medicines that can interact with prochlorperazine. Always check with your healthcare provider.

In this story, we’ll tell you quick facts to know, such as what causes a bad wheel bearing, how long you can drive on one, and the estimated replacement cost of a wheel bearing as you maintain your vehicle.

Decreased Awareness. Prochlorperazine should not be used by people who are in a coma or who have decreased consciousness.

If there is excessive play in the steering, meaning the steering seems less responsive or less precise than normal, worn bearings could be causing the problem. Also, this could be a sign the vehicle needs a wheel alignment. If you have any of the signs listed above, visit a dealer service or auto repair shop.

Injection Liquid. Injectable prochlorperazine is usually given by a healthcare provider in a hospital or clinic. You will not store it at home.